Orthokeratology vs. MiSight®: A Comparison for Myopia Control

When you are told “my child’s myopia is progressing,” the options most often named areorthokeratologyandMiSight® 1 day. Both are used to slow myopia progression, but they differ completely in how they work, in their effect on daily life, and in cost. We have summarized them based on our clinic’s information.

What Is Each Method?
Worn during sleep
Orthokeratology

Special hard contact lenses are worn only at night and removed in the morning. They reshape the cornea during sleep, so you can go through the day without glasses.

Worn during the day
MiSight® 1 day

Daily disposable soft contact lenses worn in the morning and removed at night. They are designed both to correct myopia and to slow its progression.

A Closer Comparison
Item Orthokeratology MiSight®
When worn Only during sleep (about 8 hours) While awake (daytime only)
Lens type Hard lenses (reusable) Soft lenses (daily disposable)
Vision during the day You can go about your day without glasses You wear the lenses throughout the day
Water, baths, naps No problem, since the lenses are out during the day Always remove for swimming, baths, and napsRemoval required
Eligible myopia range Generally suitable: up to about −4.00 D Beyond that, we decide case by case based on corneal shape and other factors Range studied for progression control: −0.75 to −4.00 D (spherical equivalent) Lens power manufacturing range: up to −10.00 D
Astigmatism Corneal astigmatism of −1.50 D or more can be handled with custom lenses (BOC-TD) Depending on corneal shape and the type of astigmatism, it may not be suitable → Our article: Orthokeratology for astigmatism Astigmatism up to −0.75 D can be handled Larger astigmatism may affect how things look → Our article: MiSight® and astigmatism
Approval for myopia progression control Not approved in Japan Approved only for myopia correction. Studies show a progression-slowing effect, but there is no approved indication for it in Japan. Approved for myopia progression control Approved in 2025 as Japan’s first soft contact lens for myopia progression control.
Myopia control effect (study values) Studies report slowing of axial length growth by about 30–60% (meta-analysis) Over 3 years, progression of myopic refraction was slowed by 59% and axial length growth by 52% (axial elongation 0.30 mm vs. 0.62 mm in controls; MiSight® clinical trial)
If a lens is lost ¥33,000 / lens. Until it is replaced, there is no means of daytime vision correction Because the lenses are daily disposables, losing one lets you continue from the next day’s pair
First contact lenses Hard lenses may take time to get used to Soft lenses often feel more comfortable
MiSight® is a lens “worn only while awake.”Always remove them for swimming, baths, naps, and bedtime. Not leaving them in even when dozing off is very important to protect the eyes. There is a risk of oxygen deprivation of the cornea, and in rare cases serious conditions such as corneal infection can occur.
→ Our article: The “dangers” of sleeping in contact lenses
Cost at Our Clinic (Tax Included, Self-Pay)
Orthokeratology Estimated first-year total ¥165,000
Fitting exam only (if stopped the same day)
¥5,500
1-week trial (both eyes) Includes exams, consultation, deposit, trial lenses, and initial care products. Cash only. If stopped within 1 week → ¥30,000 refunded (both eyes)
¥55,000
Main treatment, first year (both eyes) Includes lenses, 1 year of exams, consultations, and management fees
¥110,000
Second year onward (annual, both eyes) Includes exams, consultations, and management fees
¥23,100 / year
Lens replacement (about every 2 years, both eyes)
¥66,000
Warranty (within 12 months of purchase, up to 2 times in total) Power change and breakage replacement. Loss is ¥33,000 / lens.
Free
One eye only Orthokeratology treatment guide, or please ask at your visit
To be confirmed
MiSight® Pediatric Myopia Control Continuing Management Program
Initial setup cost (paid in 3 installments) Includes exams, suitability assessment, wear instruction, and the first month of lenses
¥55,000
Myopia control management program A: MiSight® + Ryjusea® Mini eye drops An approach from both optical control (lenses) and pharmacological control (eye drops) Annual management fee ¥17,600 (once a year) + lenses ¥6,800 per box (purchased every 3 months) + Ryjusea® prescription fee ¥1,100 and medication ¥13,140 (added every 3 months)
¥237,760 / year
Myopia control management program B: MiSight® alone Annual management fee ¥17,600 (once a year) + lenses ¥6,800 per box (purchased every 3 months)
¥180,800 / year
Annual and Cumulative Cost Comparison (Both Eyes)
Year Ortho-K Program A Program B
Year 1Including initial cost ¥165,000Trial ¥55,000
+ main treatment ¥110,000
¥292,760Initial ¥55,000 (includes 1 month)
+ annual management fee ¥17,600 + lenses and medication ¥220,160
¥235,800Initial ¥55,000 (includes 1 month)
+ annual management fee ¥17,600 + lenses ¥163,200
Year 2Regular year ¥23,100 ¥237,760Annual management fee ¥17,600 + lenses and medication ¥180,800Annual management fee ¥17,600 + lenses
Year 3With lens replacement ¥89,100Management ¥23,100
+ replacement ¥66,000
¥237,760 ¥180,800
Year 4 onwardRegular year ¥23,100 / year ¥237,760 / year ¥180,800 / year
3-year total ¥277,200 ¥768,280 ¥597,400
Year 1 cost
Orthokeratology
¥165,000
MiSight® Program A
¥292,760
MiSight® Program B
¥235,800
3-year cumulative cost
Orthokeratology
¥277,200
MiSight® Program A
¥768,280
MiSight® Program B
¥597,400
Both are self-pay (not covered by insurance). Orthokeratology iseligible for the medical expense deduction. MiSight® also contains an element of “treatment,” unlike ordinary contact lenses for myopia correction, and is considered likely to be eligible for the medical expense deduction. If your annual medical expenses exceed ¥100,000, you can apply when you file your tax return. Please check with your tax accountant or certified public accountant when filing.
Which Is a Better Fit?

When orthokeratology is a good fit
Children who play a lot of sports or are outdoors during the day and want to go without glasses as much as possible. It can also be used when astigmatism is present (details at the exam). However, myopia beyond −4.00 D is not eligible.

When MiSight® is a good fit
Children using contact lenses for the first time, or families who are worried about managing lenses during sleep. It can also be used for myopia beyond −4.00 D, and is an option for those who want a myopia progression control treatment approved in Japan.

With either treatment,your child’s own wish to “want to try it”is very important. If parents’ wishes run too far ahead, it can be hard to keep going.

Frequently Asked Questions
Q. Can we change methods partway through?
Yes. However, each takes time to get used to, so we recommend continuing for at least 3–6 months to evaluate the effect.
Q. Can my child do orthokeratology if they have astigmatism?
For children with strong corneal astigmatism, we can now use a custom lens (Breath-O Correct® TD). For details, please seethis article from our clinic.
Q. Do we need to take MiSight® out even for naps?
Yes, always remove them even for naps. Sleeping in soft contact lenses carries a risk of oxygen deprivation of the cornea. The same applies to baths and swimming.
Q. From what age can my child start?
At our clinic, many children start orthokeratology around age 8. It is a condition that a parent can manage the lenses during sleep. MiSight® also starts with a parent’s support.
Q. Can we use the medical expense deduction?
Orthokeratology is eligible for the medical expense deduction. When annual medical expenses exceed ¥100,000, you can receive a refund when you file your tax return. Please ask our staff for details.

* Children with myopia associated with premature birth (such as retinopathy of prematurity) or with pathologic myopia may not be eligible for these treatments. Please confirm at your exam.
* Costs and program details may change. Please contact us for the latest information.
* Costs differ if only one eye is treated. Please ask our staff for details.
* The information on this page is as of September 2026.